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DeCS
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Descriptor English:
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Vascular Endothelial Growth Factor A
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Descriptor Spanish:
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factor A de crecimiento endotelial vascular
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Descriptor Portuguese:
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Fator A de Crescimento do Endotélio Vascular
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Synonyms English:
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GD-VEGF
Glioma Derived Vascular Endothelial Cell Growth Factor
Glioma-Derived Vascular Endothelial Cell Growth Factor
Permeability Factor, Vascular
VEGF
VEGF-A
Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor-A
Vascular Permeability Factor
Vasculotropin
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Tree Number:
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D12.644.276.100.800.200
D12.776.467.100.800.200
D23.529.100.800.200
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Definition English:
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The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced. |
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History Note English:
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2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002
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Allowable Qualifiers English:
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Record Number:
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38244
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Unique Identifier:
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D042461
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Occurrence in VHL:
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Similar:
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DeCS
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